Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVGSKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFDVIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEIAESGLSLEEYYGFEGGDYVD 4OXD Chain:B ((5-186)) -------------------------------------------------------EVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFDVIGTD-DLVTEEKAAQWLLDHAADYGFVVRYLKG---ETGYMAEEWHLRYVGKEAKEIAESGLSLEEYYGFEGGDYV-

General information: TITO was launched using: RESULT: Template: 4OXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 817 -53482 -65.46 -300.46 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.91 3D Compatibility (PKB) : -65.46 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.606

(partial model without unconserved sides chains): PDB file : Tito_4OXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OXD-query.scw PDB file : Tito_Scwrl_4OXD.pdb: