Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQCYTDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG 3VQ6 Chain:A ((4-148)) PGIWQLDCTHL------EGKVILVAVHVASGYIEAEVIPA-ETGQETAYFLLKLAGRW-PV-KTVHTDNGSNFTSTTVKAACDWAGIKQEDGIP-------VIESMNKELKKIIGQV----RDQAEHLKTAVQMAVFIHNH-KRKGGIGGYSAGERIVD---

General information: TITO was launched using: RESULT: Template: 3VQ6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 626 -60676 -96.93 -439.68 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -96.93 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.258

(partial model without unconserved sides chains): PDB file : Tito_3VQ6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3VQ6-query.scw PDB file : Tito_Scwrl_3VQ6.pdb: