Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKFAGTLSGVVAE-TKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDSSMSAQEIKDFAGL- 2L6C Chain:A ((1-104)) MSAIRDITTE-------AGMAHFEGLSDAIVFFHKNLCPHCKNMEKVLDKFGARAPQVAISSVDSEAR------PELMKELGFERVPTLVFIRDGKVAKVFSGIMNPRELQALYASI

General information: TITO was launched using: RESULT: Template: 2L6C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 428 -20505 -47.91 -201.03 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -47.91 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.578

(partial model without unconserved sides chains): PDB file : Tito_2L6C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2L6C-query.scw PDB file : Tito_Scwrl_2L6C.pdb: