Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDMTKIALLSDIHGNTTALEAVLADAR-QLGVDEYWLLGDILMPGTGRRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEEIEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLV--------------------THPPCDIAVYGHIHQQLLRY-GTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRRVDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLKSGND 2QJC Chain:A ((17-227)) -VTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRL-GAYSVLGNHDAKLLKLVKKL-------------SLAPLAQSIPTDVETYLSQLPHIIR--IPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVY------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2QJC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 825 -19216 -23.29 -113.70 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -23.29 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_2QJC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QJC-query.scw PDB file : Tito_Scwrl_2QJC.pdb: