Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYKSIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKFWNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGDFATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKLEIVYVK 1P9H Chain:A ((32-220)) PNLTAVQISPNADPALGLEYGLNASAKGIH-----------------SIAIGATAEAAKGAAVAV------------GAGSIATGVNSVAIGPLSKALGDSAVTY------GAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAAN----------HGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEK

General information: TITO was launched using: RESULT: Template: 1P9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1041 -43703 -41.98 -244.15 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -41.98 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.193

(partial model without unconserved sides chains): PDB file : Tito_1P9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P9H-query.scw PDB file : Tito_Scwrl_1P9H.pdb: