Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDQYQAFTQSPIGKFVVKNLGLPSPVVLERFESAQPVVKGAVLVGAAPSSVLSGAIAQVLSNIHADSYVGNNVALQQEAAKVGLNLRPFNAGDKESKFKAVVFDASGIQNSEQLNELYKFFNPIARQVATSGRVIVIGTTPETAKTIKQAIAQRALEGFIKSVGKEFKKGITAQVVYVD---EGAAANLESTLRFLLSPRSAYVSGQVIRVSKADVVD-VDWAKPLAGKTALVTGASRGIGEAIAHVLARDGAHVICLDVPQQQADLDRVAADIGGSTLAIDITAADAGEKIKAAAAKQGG--LDIIVHNAGITRDKTLANMKPELWDLVININLSAAERINDYLLENDGLNANGRIVCVSSISGIAGNLGQTNYAASKAGVIGLVKFTAPILK-NGITINAVAPGFIETQMTAAIPFAIREAGRRMNSMQQGGLPVDVAETIAWFASTASTGVNGNVVRVCGQSLLGA 3Q6I Chain:B ((12-446)) --------------SFLARQLG-PQPETLRRYRAGEPPLTGSLLIGGA---------GRVVEPLRA--------ALEKDYDLVG------------DSFGGLVFDATGITEPAGLKGLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGKELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADDSTPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVESAAENLAETASKVGGTALWLDVTADDAVDKISEHLRDHHGGKADILVNNAGITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIGEGGRVIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPGFIETQMT-AIPLATREVGRRLNSLLQGGQPVDVAEAIAYFASPASNAVTGNVIRVCGQAMIGA

General information: TITO was launched using: RESULT: Template: 3Q6I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2471 -115586 -46.78 -276.52 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.84 3D Compatibility (PKB) : -46.78 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_3Q6I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q6I-query.scw PDB file : Tito_Scwrl_3Q6I.pdb: