Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDLHRLSIRELAKGLSQAKFSSRELTEHYLKRIAKIDPQVKSYVTVTPEQALCEADAADAALKAGNATALTGIPLAHKDIFCTKGIKTTAGSKMLDNFISPYDATVVEKTKAAGLVTLGKVNMDEFAMGSTSESSYVGATSNPWALDHVPGGSSGGSAAAVAADLAPFATGTDTGGSIRQPASFCGLTGLKPTYGRVSRFGIIAYASSLDQAGPMARSAEDCAYLMNVIAGHDAKDSTSVKKEVDDYVANLNNTSVKGLRIGIPKQYFNVAGLDAEVKARVEESLKKLEEMGAKLVEIDLNMTEAYVPTYYLIAPAEASSNLSRYDGVRYGYRCENPADLMDLYKRSRSEGFGPEVQRRILIGTYALSAGYYDAYYVKAQKVRRLIQQDFLKAFENVDVIAAPAAPTTAYKIGASLD-PVEMYLGDIYTIAVNLAGLPAINAPVGFDKDNLPVGLQLIGNYWSESQLLSIVHQYQQNTDWHTKRAAIAEENA 3H0R Chain:D ((2-474)) ---LWKKSLSELRELLKRGEVSPKEVVESFYDRYNQTEEKVKAYITPLYGKALKQAESLKE-----RELPLFGIPIAVKDNILVEGEKTTCASKILENFVAPYDATVIERLKKAGALIVGKTNLDEFAMGSSTEYSAFFPTKNPWDLERVPGGSSGGSAASVAVLSAPVSLGSDTGGSIRQPASFCGVIGIKPTYGRVSRYGLVAFASSLDQIGVFGRRTEDVALVLEVISGWDEKDSTSAKVPVPEWSEEVKK-EVKGLKIGLPKEFFEYE-LQPQVKEAFENFIKELEKEGFEIKEVSLPHVKYSIPTYYIIAPSEASSNLARYDGVRYGYRAKEYKDIFEMYARTRDEGFGPEVKRRIMLGTFALSAGYYDAYYLKAQKVRRLITNDFLKAFEEVDVIASPTTPTLPFKFGERLENPIEMYLSDILTVPANLAGLPAISIPIAW-KDGLPVGGQLIGKHWDETTLLQISYLWEQKFKHYEK---------

General information: TITO was launched using: RESULT: Template: 3H0R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 3169 -172849 -54.54 -366.21 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain D : 0.88 3D Compatibility (PKB) : -54.54 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_3H0R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H0R-query.scw PDB file : Tito_Scwrl_3H0R.pdb: