Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQLDQRPIIALDFSTRQEVEDFL-RFFPKEEKLFVKIGMELFYQEGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAAMRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYA----SCAKKAGLDGVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGRPITQSTNPYKAYQTIQTEWS 1EIX Chain:C ((18-238)) --------VVALDYHNRDDALAFVDKIDPRDCRL--KVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMTAAREAL---VPFGKDAPLLIAVTVLTS-----MEASDLVDLGMTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKAIN----

General information: TITO was launched using: RESULT: Template: 1EIX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1163 -12695 -10.92 -58.77 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain C : 0.82 3D Compatibility (PKB) : -10.92 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_1EIX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EIX-query.scw PDB file : Tito_Scwrl_1EIX.pdb: