Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGARRVPKYFPSMA 4ZEP Chain:B ((30-184)) -------QVEGAWNEDGKGLSVWDV-------FAKQPGRTFKGT--------NGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGN-GAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISF------------------------

General information: TITO was launched using: RESULT: Template: 4ZEP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 644 -62082 -96.40 -400.53 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : -96.40 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_4ZEP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZEP-query.scw PDB file : Tito_Scwrl_4ZEP.pdb: