Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVTDTKLTDVKIVEMDVFG----------DHRGFFTESYSKAKF-AEHGLKYDFVQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFILSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWP-IDPSRAIMSEKDHRHPTLKEFEAENPFVYGEI 2IXC Chain:D ((1-184)) ----------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSS-AGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASG-------

General information: TITO was launched using: RESULT: Template: 2IXC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 918 -5896 -6.42 -34.28 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain D : 0.80 3D Compatibility (PKB) : -6.42 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.440

(partial model without unconserved sides chains): PDB file : Tito_2IXC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IXC-query.scw PDB file : Tito_Scwrl_2IXC.pdb: