Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGKL-GAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 2DX0 Chain:A ((24-109)) WFHKKVES-----RTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYYLTDNLTFNSIYALIQHY

General information: TITO was launched using: RESULT: Template: 2DX0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 302 -12948 -42.87 -152.32 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : -42.87 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.743

(partial model without unconserved sides chains): PDB file : Tito_2DX0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2DX0-query.scw PDB file : Tito_Scwrl_2DX0.pdb: