Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTYEGNL-VANNIKIGIVVARFNEFITSKLLSGALDNLKRENVNEKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA 1C2Y Chain:F ((1-154)) MNELEGYVTKAQSFRFAIVVARFNEFVTRRLMEGALDTFKKYSV-NEDIDVVWVPGAYELGVTAQALGKSGKYHAIVCLGAVVKGDTSHYDAVVNSASSGVLSAGLNSGVPCVFGVLTCDNMDQAINRAGGKAGNKGAESALTAIEMASLFEHHL-

General information: TITO was launched using: RESULT: Template: 1C2Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 865 -52340 -60.51 -342.09 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain F : 0.87 3D Compatibility (PKB) : -60.51 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.587

(partial model without unconserved sides chains): PDB file : Tito_1C2Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1C2Y-query.scw PDB file : Tito_Scwrl_1C2Y.pdb: