Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----WFFKNLSRKDAERQLLAPGNTHGSFLIRESEST-AGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGSYISPRITFPGLHELVRHY----------------- 1LKK Chain:A ((1-105)) LEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTA-GSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQT

General information: TITO was launched using: RESULT: Template: 1LKK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 266 21649 81.39 264.01 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.90 3D Compatibility (PKB) : 81.39 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.875

(partial model without unconserved sides chains): PDB file : Tito_1LKK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1LKK-query.scw PDB file : Tito_Scwrl_1LKK.pdb: