Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence TPPGSPSARLAGTSNARLAG------------ISNTNPPGGAPRPRQQCFLSADLGPDVMGQPTLLEATPFVND---MFDFHGYRCQMGKDCSHVRCRGFPAAFKMTARNYPDGKGPLGTSAGDSF-VPGPVVKVYPAPR 5FAA Chain:A ((149-271)) TTYERTFVKKDAETKEVLEGAGFKISNSDGKFLKLTDKDGQSVSIGEGFIDVLANNYRLTWVA-ESDATVFTSDKSGKFGLNGFADNTTT-------------YTAVETNVPDGYDA---AANTDFKADNSSSDILDAPS

General information: TITO was launched using: RESULT: Template: 5FAA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 455 27300 60.00 255.14 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 60.00 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.053

(partial model without unconserved sides chains): PDB file : Tito_5FAA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FAA-query.scw PDB file : Tito_Scwrl_5FAA.pdb: