Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSLNSSYGRSQAVPLSVFEQSKDAHIIRSDEEAIEIAKQLAQEFATEASDRDRERRLPLNEIQQFSQSGLWAITVPKQFGGAQVKYRTLAEVIKTIASVDSSLAQLPQNHLAFIEHLRLDAKPEQQQFFFNLVLRGIRF-GNAFSEKHSKTVADLTTTLRKTEHG-YEINGKKFFATGALLAHWIPIVAVNELGQP-----YAALVPRETSGVNIINDWSGFGQRTTASGTVELNQVPVREEYLVPIYQAF-------ESPTPAGAISQFIQAAVDAGIARGAIEETIQYVKNHSRAWIDSGLEKASDDPYTIANIGDLKIKLRAA-----------EAVLDLAGDAIDQAIANTTEEHVNQATLLVAEAKVLTTEIAILAANKLFELSGTRSTLSELNLDRHWRNARTHTLHDPVRWKYHIVGNYYLNGVQPPRHAWS 3X0Y Chain:F ((18-411)) -------------------------------NDPVAVARGLAEKWRATAVERDRAGGSATAEREDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLTNAPMIELIGSQEQEEHLYTQIAQNNWWTGNASSENNSH-VLDWKVRATPTEDGGYVLNGTKHFCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDFHNVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREYTRTQARPWTPAGIQQATEDPYTIRSYGEFTIALQGADAAAREAAHLLQTVWD-KGDAL-------TPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSLHDPVSYKIADVGKHTLNGQYP------

General information: TITO was launched using: RESULT: Template: 3X0Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 1962 -14742 -7.51 -39.95 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain F : 0.76 3D Compatibility (PKB) : -7.51 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.417

(partial model without unconserved sides chains): PDB file : Tito_3X0Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3X0Y-query.scw PDB file : Tito_Scwrl_3X0Y.pdb: