Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINCGAKMLIQRGGLKVVAGLGISG-VSAVNFLHEQGYQVAVTDSRPTPPGHDQIPA-GVKTSFGQLDQELLLQAEEIILSPGLAPQLPEIQAAIAKGISVVGDIQLLRRAT-DVPIVAITGSNAKSTVTTLIGLMAKDAGKK-VAVGGNLGRPAL-DLLKDQPELLVLELSSFQLETTSHLNAEVAVVLNMSEDHLDRHG-NMLGYHQAKHRIFQGAK---KVVFNRDDALSRPLVPD-TTPMQSFGLNAPDLNQYGVLR-DA--DGTLWLARGLQRLIKSSDLYIQGMHNVANALACLALGEAIGLPMESMLETLKQFKGLEHRCEYVK----TVHDVRYYNDSKGTNVGATLAAIDGLGAAIEVKKGKVALILGGQGK--GQ-DFSPLRSSIEKYAKVVVLI-----------GEDAPVIEQAIQGAT--KILHAATLKEAVELCQRETQAEDVVLLSPACASFDMFKSYNDRGQQFVACVNSLV 1GQY Chain:B ((14-466)) --------EMRRVQQIHFIGIGGAGMSGIAEILLNEGYQISGSDIADGVV-TQRLAQAGAKIYIG-HAEEHIEGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAMISMIYTQAKLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDAS-FLHLQPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKVGRQVITYGFSEQ--ADYRIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNATAALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDDY-GHHPTEVGVTIKAAREGW--GDKRIVMIFQPHRYSRTRDLFDDFVQVLS-QVDALIMLDVYAAGEAPIVGADSKSLCRSIRNLGKVDPILVSDTSQLGDVLDQIIQDGDLILAQGAGSVSKIS------------------

General information: TITO was launched using: RESULT: Template: 1GQY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2343 -6011 -2.57 -14.31 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : -2.57 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.505

(partial model without unconserved sides chains): PDB file : Tito_1GQY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GQY-query.scw PDB file : Tito_Scwrl_1GQY.pdb: