Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINKKPRIPSPVQIPEHLSFLQGFRDYLVAQTVSPHTRNAYLSDLIQCSEIHKKNRLPDWTSDDISDVLIELTKVGKSPRSIARCLSALRQFYKSLREQKLRSDNPVATHHSPKIGRALPKDLSEEDVEALIQAPDITTALGLRDRAMFEVLYACGLRVSELLNLRLELINLKQGYLRI-TGKGNKERLVPLGQYACDWVERYLNEARPQLYKSSTDYLFLTQHGGIMSRQNFWYAIKRYALQANIQ--AELSPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVAQVRMQQLHEKHHPRG 1AIH Chain:C ((5-161)) ------------------------------------------------------------------------------------------------------------------------AFLYERDIYRLLAECDNS--RNPDLGLIVRICLATGARWSEAETLTQSQVMPY--KITFTNTKSKKNRTVPISDELFDMLPKK------------RGRLFND----------AYESFENAVLRAEIELPKGQLTHVLRHTFASHFMMNGGNILVLKEILGHSTIEMTMRYAHFAPSHLESAVK------

General information: TITO was launched using: RESULT: Template: 1AIH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 625 -58594 -93.75 -380.48 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain C : 0.64 3D Compatibility (PKB) : -93.75 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.464

(partial model without unconserved sides chains): PDB file : Tito_1AIH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AIH-query.scw PDB file : Tito_Scwrl_1AIH.pdb: