Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNAPVALTPELLTQLTAIVGENRIKTDADSLENWGKDHTKHFNPNPSVIVFPSTTEQVQEVVKLANQFNIAITPSGGRTGLSAGAV-----ATKGEIVISMDKMNQILEFFPADRMVRVQAGVVTEQLQNYAEEQGMYYP--VDFASAGSSQIGGNIGTNAGGIKVIKYGMTRNWVLGLTVV-----------------TGKGDILRLNKGMIKNA-----------TGYALQH----------------LFIGGEGTLGLVTEAEIKLE--RQPQNLQVLVLGVPDFDAVMPVLHAFQKDID--LTAFEFFGELTMQKVLDRGHVQRPFETQCPFYVLLEFEAPYEPIIDKAMEIFEHCMEQGWVLDGVMSQSLDQVESLWRLREDISESIAPFIP-YKNDISVLITHVPAFIREIDAIVQE-----NYPYFEICWFGHIGDGNLHLNILKPENLTKDEFFAKCQVVNKYVFDTVKKYDGSISAEHGVGMTKKPYLEYSRSAEEIEYMKALKKVFDPKGIMNPG-----KLFDL 1F0X Chain:A ((9-567)) -------NKAFLNELARLVGSSHLLTDPAKTARYRKGFRSG-QGDALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDVVIISTLRLDKLHVL-GKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGG-ICNNSGGSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRHDGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIA-ELPPRMKNWRDKYEHHLLLKMA---GDGVGEAKSWLVDYFKQA--EGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSDEVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVD-------VHALKEQMLELLQQRGAQYPAEHNVGHLYKAP----------ETLQKFYRENDPTNSMNPGIGKTSKRKNW

General information: TITO was launched using: RESULT: Template: 1F0X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2479 15991 6.45 36.68 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 6.45 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.471

(partial model without unconserved sides chains): PDB file : Tito_1F0X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1F0X-query.scw PDB file : Tito_Scwrl_1F0X.pdb: