Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKSPGFTIVELTITLVILVIMSVIAIPLYHQFMASVELKNTLRILTIHIQKAKYDAIIRHKNVVLCPSSDQLVCNTNWDNRIISFVDNN--RNLQHDL-NEELLA--SIDLNHHYGSMKLQ----RFGKKQNSIIFQGNSGLPIESNGSFIYCSYDQLKKREFGLSRI 2KNQ Chain:A ((6-116)) -------------------------------EDVANTRARETAARFTAALELAIDRATLSGQPVGIHFSDSA----------WRIMVPGKTPSAWRWVPLQEDAADESQNDWD-EELSIHLQPFKPDDSNQ-PQVVILAD-GQIT--PFSLLMANAG------------

General information: TITO was launched using: RESULT: Template: 2KNQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 378 -14992 -39.66 -146.98 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -39.66 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.308

(partial model without unconserved sides chains): PDB file : Tito_2KNQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2KNQ-query.scw PDB file : Tito_Scwrl_2KNQ.pdb: