Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPAVKSNRPVNLSMGQVLAVNLRSPV-AIASILHRLSGVIVFLLVPVLLWILDKSLSSPEGFDYVKNVVFGNILVRFVVWVFVAGLIFHFIAGVKHLLADLGFAEE-LQSGRIAATISLILSVVAIIAAFVWIVF 2WDV Chain:G ((8-119)) ------QRPVNLDLQ-----TIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQA-SAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVV-----------

General information: TITO was launched using: RESULT: Template: 2WDV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 225 -35454 -157.57 -322.30 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain G : 0.79 3D Compatibility (PKB) : -157.57 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.247

(partial model without unconserved sides chains): PDB file : Tito_2WDV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WDV-query.scw PDB file : Tito_Scwrl_2WDV.pdb: