Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPKRRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER----- 2L6M Chain:A ((21-121)) MKGDIEHKVYQLLKDQGCEDFG-TKCVIEEVKSSHKTLLNTELHLTKYYGFSFFRHGNIVAYGKSRK----VANAKYIMKQRLLKLLEDKSNLLLYSCNCKFSKKK

General information: TITO was launched using: RESULT: Template: 2L6M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 363 -21615 -59.54 -225.15 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -59.54 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.218

(partial model without unconserved sides chains): PDB file : Tito_2L6M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2L6M-query.scw PDB file : Tito_Scwrl_2L6M.pdb: