Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MSQKLYNMKFAAVYLALIAKV-ERKGGKAESVHQVTSWLTGYEVSDVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDWLAKGKTSQQVLEKYEKHK 4HR1 Chain:A ((2-119)) FNGAQTVIQKISWLRTAIAFLKGYMETTGATKKELEQVEKLKE--RVDEIATAVNWDV-YAQYARGDFNLLSDDEYKEIQKALLVLEDIKEQIIVEMLRVGLAQGQMGTLKISDYLDSLDS---

General information: TITO was launched using: RESULT: Template: 4HR1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 337 -21891 -64.96 -192.02 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -64.96 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.307

(partial model without unconserved sides chains): PDB file : Tito_4HR1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HR1-query.scw PDB file : Tito_Scwrl_4HR1.pdb: