Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------------------------------------MGLFTLKEVSHYLIENKNMAWS---------------ITMCLVAVLLTI--FILNLILGLLVHFFDYSEPIWWHALSPYFIALLLFIMVWSVVTELYILRKGGHSLAKQLKARRLVKGESTPEEHAALKITEHLAQTFSLNVPTLYVLPDEVGVNALTAGFHSNDIVIILTWGALQNLDELE-LYGLLGHEFNQILSG--EAVENTKLKILYSGLTTFSQWGSKLAKQGFKRYSPGYKHKFETVFVAVGGVI------WLAGSLGVLITRFIKYLTLSGRT---FRNDQKTMRLLKN--------STNAQTLLR---IYVHHSGSQIHSAYSESIAHMCFANSLSPQSWMNIHPSIRERIYELNPTLLQDLQLENLKKLRNRPLFILFHVLEESETEIYTPWSSPQPLPLLRLSPISFALN-----------DAIKPLSSDIRR-NKKRPELIQRALQTATGSREVMV---AILMIRQYREFIPQDAPVSHAIVDALLNLDGRIH-----------IQIFHDACKNIGHMPASIARQFLTKLALIIQEDGEIGLLDALLLERVKYELNLMPLHLPTAFEEVKPQIVRLIDALLHVQQIN-SPNQLEVRKRILR-------------SLLNPDEMHIYDEISDEPLDLAEILNDIAGLLLRDRLSILAIVEMCLWSDRIITQDELDVLELLYWRFGFES---------DEIVEQMQKKNSVMII---------------------------------------------------------------------------------------------------------------------------------------------------------------- 1Z3H Chain:A ((2-959)) SDLETVAKFLAESVIASTAKTSERNLRQLETQDGFGLTLLHVIASTNLPLSTRLAGALFFKNFIKRKWVDENGNHLLPANNVELIKKEIVPLMISLPNNLQVQIGEAISSIADSDFPDRWPTLLSDLASRLSN----DDMVTNKGVLTVAHSIFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITANENNKASLNILFDVLLVLIKLYYDFNCQDIPEFFEDNIQVGMGIFHKYLSYSNPLLEDPDETEHASVLIKVKSSIQELVQLYTTRYEDVFGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVTRIPKYFEIFNNESAMNNITEQIILPNVTLREEDVELFEDDPIEYIRRDLEGSDTDTRRRACTDFLKELKEKNEVLVTNIFLAHMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNAGVSSTNNLLNVVDFFTKEIAPDLTSNNIPHIILRVDAIKYIYTFRNQLTKAQLIELMPILATFLQTDEYVVYTYAAITIEKILTIRESSNSTEILLKNLIALILKHGSSPEKLAENEFLMRSIFRVLQTSEDSIQPLFPQLLAQFIEIVTIMAKNPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSMMPTFLTVFSEDIQEFIPYVFQIIAFVVEQSATIPESIKPLAQPLLAPNVWELKGNIPAVTRLLKSFIKTDSSIFPDLVPVLGIFQRLI-ASKAYEVHGFDLLEHIMLLIDMNRLRPYIKQIAVLLLQRLQNSKTERYVKKLTVFFGLISNKLGSDFLIHFIDEVQDGLFQQIWGNFIITTLPTIGNLLDRKIALIGVLNMVINGQFFQSKYPTLISSTMNSIIETASSQSGSHFSKLVSISEKPFDPLPEIDVNNGVRLYVAEALNKYNAISGNTFLNTILPQLTQENQVKLNQLLVG

General information: TITO was launched using: RESULT: Template: 1Z3H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2826 -96060 -33.99 -152.72 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -33.99 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.256

(partial model without unconserved sides chains): PDB file : Tito_1Z3H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Z3H-query.scw PDB file : Tito_Scwrl_1Z3H.pdb: