Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------MMRTMLISLSVGVYMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPA--LTSYNKVSYPPTINHYWLIPNKTLWTSETGSSV----PLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQVSYVYE---KDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTTNTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVTKSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTVITHFIDSQTNKELQAETHMSSVNRIPDLRLPA---EFSDRVPNIDLS----TYEQN---GKVTSI--SDWMQANGLDRK-----SHWSEILEVLHSELM------------------NNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNEKINKEELIQSATNSLGKP-VPLKDVSVTINEVP-LEDGYLTKQTGDFTIM---YSYHDPYSL----QELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVS------------------PTGKVK--------------QTRSLELARISRKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETKKKRLSTIDSTDEHLQPQ-VPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDADDWF-------------- 2QZV Chain:A ((3-779)) GCGCPCGCGAMATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNE---RVLFAPVRMVTVPPRHYCIVANPVSRDTQSSVLFDITGQVRLRHADQEIRLAQDPFPLYPQVVLPNTALHLKALLDFEDKNGDKVMAGDE----WLFEGPGTYIPQKEVEVVEIIQATVIKQNQALRLRARKECFDREGKGRVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRALQNFRDLRGVLHRTGEEWLVTV------QDTEAHVPDVYEEVLGVVPITTLKSFFLQ----PGERLERGIQDVYVLSEQQGLLLKALQPLEEGESEEKVSHQAGDCWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPSGVEELLNLGHDPLADRGQKGTAKPLQPSAPRNKTRVVSYRVPHNAAVQVYDYRAKRARVVFGPELVTLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFELKNRNDPAEAAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRMAVFGFEMSEDTGPDGTLLPKARDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELIYARAQLEL

General information: TITO was launched using: RESULT: Template: 2QZV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1914 98186 51.30 153.90 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 51.30 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.101

(partial model without unconserved sides chains): PDB file : Tito_2QZV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QZV-query.scw PDB file : Tito_Scwrl_2QZV.pdb: