Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKPEYLIHAEHLTVILCPLEKQH-KILEHL---KK--------------EVL-VAKLDNFAIIQKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISP----------SLLNCAAAELTSFEKVKLQLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSPYIDRLEPAG 4MYC Chain:C ((454-643)) -NASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGRILINGRDIKEYDIDALRKVIGVVPQDTPLFND-TIWENVKFGRIDAT-DEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTIA--DADKII---

General information: TITO was launched using: RESULT: Template: 4MYC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 607 2464 4.06 15.30 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain C : 0.65 3D Compatibility (PKB) : 4.06 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.472

(partial model without unconserved sides chains): PDB file : Tito_4MYC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MYC-query.scw PDB file : Tito_Scwrl_4MYC.pdb: