Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDTSKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARFAAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAY-VPQNRERIFLIGHSRDACTEQV-FPIIGSSPTS-DQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGDEGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQEVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQGFPDWAFDRASQVN-SDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL 2UYH Chain:A ((12-318)) LRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYEMNFGEKPE---GDITQVNEKTIPDH---DILCAGFPCQAFSIQGKQKGFEDSRGTLFFDIARIVREKKPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAKVLNALDYGIPQKRERIYMICFRNDLNIQNFQFP----KPFELNTFVKDLLLPDSEVEHL---VIDRKDLVMT---NQEIEQTTPK----TVRLGIVGKGGSGERIYSTRGIAITLSAYGGG----------------------------------IFAKTGGYLVNG----------KTRKLHPRECARVMGYPD-----SYKVHPSTSQAYKQFGNSVVINVLQYIAYNI--------

General information: TITO was launched using: RESULT: Template: 2UYH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1739 -103062 -59.26 -340.14 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -59.26 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.425

(partial model without unconserved sides chains): PDB file : Tito_2UYH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2UYH-query.scw PDB file : Tito_Scwrl_2UYH.pdb: