Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence CVIGLTFNGNWV----------PNNRFVISPGGKFSFIA-NYVIIPVRLDESCHWHQDLAENAKPVII------PSGY--------------------GIKSCDEGDFVNNQCQEPPKRTSI--GGTKVYAFS 1PEW Chain:A ((1-109)) ---------NFMLNQPHSVSESPGKTVTISCTRSSGNIASNYV----------QWYQ---QSAPITVIYEDNQRPSGVPDRFAGSIDRSSNSASLTISGLKTEDEADYY---CQSYDARNVVFGGGTRLTVLG

General information: TITO was launched using: RESULT: Template: 1PEW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 189 7940 42.01 115.07 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 42.01 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.067

(partial model without unconserved sides chains): PDB file : Tito_1PEW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PEW-query.scw PDB file : Tito_Scwrl_1PEW.pdb: