Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDLPNPVLAKVTERVIARSQKTRSAYLQRIEHAQGKFPARGALSCANLAHGFAGMEDNEKLIIKVGR-EPNIGIVSSYNEMLSAHAPYKTFPDIIKTAARENGGVAQFAGGVPAMCDGITQGNASMELSLFSRETIAMGTAIALSHNMFDAALCLGVCDKIVPGLLIGALQFGYLPTIFVPAGPMSSGLSNDDK-------AKIRQQFATGQVGRDALLEAESAAYHGQGTCTFYGTANSNQMLMEVMGLHLPSAAFVHPHTPLRDALTAEAAKRVLDLTAEQGNYTPIGHVIDEKAIINGIVALLATGGSTNHTLHLIAIAHAAGILIDWDDFDELSAVVPLLAKIYPNGKADVNHFQAAGGVAFLIRNLLEAGLLHNDVKTVAGKGL-QHYTKEPKLIDGKLTWVDGVVQSLDDKVLRSIDAPFQPDGGLRLMQGRLG--RGVIKISAVAPEHRKVKAPAIVFDSQEAVQAAFDR--GELHRDFIAVVRFQGARA-NGMPELHR---LTPVLGVLQDQGFHVALVTDGRMSGASGKVPAVIHLSPEALLNGPIGKVQTGDMLIIDAEAGVLDIELDEQTWQSRPVAQPEHQAENEVGFGRELFGVFRAAAAPAEHGASVFGALVGEEPQGQI 5J84 Chain:H ((14-579)) ----------------------AEWPRKLRSQEWYGGTS---RDVIYHRGWLKNQGYP-HD---LFDGRPVIGILNTWSDMTPCNGHLRELAEKVKAGVWEAGGF-PLEVPVFSASENTFRPT-----AMMYRNLAALAVEEAIRGQPMDGCVLLVGCD-TTPSLLMGAASC-DLPSIVVTGGPMLNGYFRGERVGSGTHLWKFSEMVKAGEMTQAEFLEAEASMSRSSGTCNTMGTASTMASMAEALGMALSGNAAIPGVDSRRKVMAQLTGRRIVQMVK---DDLKPSEIMTKQAFENAIRTNAAIGGSTNAVIHLLAIAGRVGIDLSLDDWDRCGRDVPTIVNLMPSGKYLMEEFFYAGGLPVVLKRLGEAGLLHKDALTVSGETVWDEVKDVV---------------NWNEDVILPAEKALTSSGGIVVLRGNLAPKGAVLKPSAASPHLLVHKGRAVVFEDIDDYKAKINDDNLDIDENCIMVMKNCGPKGYPGMAEVGNMGLPPKVLK--KGILDMV-RISDARMSGTA-YGTVVLHTSPEAAVGGPLAVVKNGDMIELDVPNRRLHLDISDEELARRLA-EWQPNH---DLPTSGYAFLHQQHVEGADTGADLDFLKGCR------

General information: TITO was launched using: RESULT: Template: 5J84.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain H - contact count / total energy / energy per contact / energy per residue : 3546 -11017 -3.11 -20.10 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain H : 0.73 3D Compatibility (PKB) : -3.11 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.459

(partial model without unconserved sides chains): PDB file : Tito_5J84.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5J84-query.scw PDB file : Tito_Scwrl_5J84.pdb: