Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIFSTNTCPVPNDLESVIHHKDEVPAELCGMSEQQVQKIWKSIESLYKTGNYPLITFCLRRQGKILLNRSIGYAQGNSPAGLQENALIATPDTPVCLFSASKMITAMLIHLLDEKGEINLLDPVSYYIPEYGVNGKRRATIFHLLSHRGGIPYVDGDVTPELL----------FDKDEILRRLYAARP--VSPAGNHLAYHAVTAGYILGEIIERVTGQDLRKFVHETIEKPMDMPYFNYGLKPEYRAEVALNCATGLHPRLGTDHYLNHVLGGGLQLAVDVTNDSRFMDTICPAGNIYTSAEQAGRFFEMLLSGGSYQGKQILSEKTIFRATLPTTGVNIDRTLLIPMRYALGPMLGSNPVGLFGPMTGQAFGHLGFSNILCWADPERDISVSLLTTGKSVVGTHLPALANLLYQISIQCPRIPRDQRRSLFGS---------DSHETDLV----------------------------------------------------------------- 2QMI Chain:A ((1-447)) ----------------------------------MDVGKLESFIVEKMAERKVPGISISIIKDGDVVYAKGFGYRN-------VEARLPSTPETIYGIGSITKSFTALAIMKLVEEGGLSLDDPVEKFVNIKLRPFGEPVTVHHLLTHSSGIPSLGYAEAFIDGMVGGDNWLPVSTPEETIAFARDMEKWAVAKPGERFFY-LNTGYVLLGKIIEKVSGVSYEEYIKKKILEPLGMNRSYFFKEEVEKDK---DVAMGYILDKE-----------------GRLVPQPFPYGITADGGLLSSVLDLAKYLKMYIERD----ESIVSKEYIEKMETSYIKVPWEIFG--GEGYGYGLIIYPNFLGEKLVGHSGSVG--MYTGYIGYI-PEKKIGVAVLENSSGYPPSYIAMYALALLLGKNPEKELPFIYRERILKKVEGRYMGYKGTIKFEVKVDGDVVYLRALGRAFTYTIPLFPEVLEEDFIKCYTLSNGRKMYAEFYIKDNKVDLIFERYRLIKS

General information: TITO was launched using: RESULT: Template: 2QMI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2177 -102290 -46.99 -283.35 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -46.99 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_2QMI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QMI-query.scw PDB file : Tito_Scwrl_2QMI.pdb: