Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLEKILQSQGFGSRKYCQQLIKNGSVSIDGEVVSDLKKQFSPENFEFSVFGQNYQYREKIYIALRKPQGFECSHHPQHHQSVFSLLPETM-IHRGVQAVGRLDQDTTGLLLLTDDGKYLQVLTHPR--KHVPKVYHVTTYDPVTPE--QIEMLI------QGVNLHQEKEVFAAT--DVALL----GTHQLTMTIHQGVYHQVKRMIAAVGNKVEKLHRHQIGQLVLPEIEDGDWVYLSEQEKQLAQNII 1V9K Chain:B ((3-174)) -----------------------------------------------------VIMYEDDHILVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSALRSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSETRFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDRE--------------------------

General information: TITO was launched using: RESULT: Template: 1V9K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 629 -11898 -18.92 -76.76 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain B : 0.61 3D Compatibility (PKB) : -18.92 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.228

(partial model without unconserved sides chains): PDB file : Tito_1V9K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V9K-query.scw PDB file : Tito_Scwrl_1V9K.pdb: