Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------PEGTVALQAR--YPANNKKAGKVNAAANNGTAAGGNVNGTADFGKCKPTMSFKTGRPGRKATEGTFLPDDELVAKGQQDALNPNIITN--RICDQLTNVCSANAAAKTQCAAAKAMVSSLGTKDSSTADAFNKALGF 1E8E Chain:A ((1-124)) DVTNAEKLVYKYTNIAHSANPMYEAPSITDGKIFFNRKFKTPSGKEAACASCHTN-NPANVGKNIVTGKEIP-----PLAP--------RVNTKRFTDIDKVEDEFTKHCNDILGADCSPSEKANFIAYLLTETKPTK---------

General information: TITO was launched using: RESULT: Template: 1E8E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 314 29370 93.54 267.00 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 93.54 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.241

(partial model without unconserved sides chains): PDB file : Tito_1E8E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E8E-query.scw PDB file : Tito_Scwrl_1E8E.pdb: