Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------------GCQIE---LLNINQQVVDSVCIPHDGVRPMRDATAPKGV-INYAVKVNSSCGAGLAAGN---LANGASL-RNA--GPY----------------------------------------------------------------------------------------------------------------- 1HM9 Chain:A ((261-468)) VSFVNPEATYIDIDVEIAPEVQIEANVILKGQTKIGAETVL-TNGTY-VVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYATRLPHHPKNQ

General information: TITO was launched using: RESULT: Template: 1HM9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 339 7249 21.38 109.83 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : 21.38 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_1HM9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HM9-query.scw PDB file : Tito_Scwrl_1HM9.pdb: