Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------NCIANILNI-NQAIVGSGCIPAGGTAFVAANGA-NWLISASRS---------------CGLGLS------------- 1CR5 Chain:A ((5-93)) TRHLKVSNCPNNSYALANVAAVSPNDFPNNIYIII--DNLFVFTTRHSNDIPPGTIGFNGNQRTWGGWSLNQDVQAKAFDLFKY

General information: TITO was launched using: RESULT: Template: 1CR5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 110 -9735 -88.50 -216.33 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -88.50 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.423

(partial model without unconserved sides chains): PDB file : Tito_1CR5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CR5-query.scw PDB file : Tito_Scwrl_1CR5.pdb: