Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSSGPGPRFLLLLPLLLPPAASASDRPRGRDPVNPEKLLVITVATAETEGYLRFLRSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYADREDMIIMFVDSYDVILAGSPTELLKKFVQSGSRLLFSAESFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFATTIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLSLNLDHKSRIFQNLNGALDEVVLKFDRNRVRIRNVAYDTLPIVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCNQDRRTLPGGQPPPRVFLAVFVEQPT-PFLPRFLQRLLLLDYPPDRVTLFL--HNNEVFHE-----PHIADSWPQLQ---D--HFSAVKLVGPE-EALSPGEARDMAMDLCRQDPECEFYFSLDADAVLTNLQTLRILIEE-----NRKVIAPMLSRHG-KLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPY-ISQAYVIRGDTLRMELPQRDVFSGSDTDPDMAFCKSFRDKGIFLHLSNQHEFGRLLATSRYDTEHLHPDLWQIFDNPVDWKEQYIHENYSRALEGEGIVEQPCPDVYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWALLHPGRLTHYHEGLPTTWGTRYIMVSFVDP 4P02 Chain:A ((138-390)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKG----ELVVVFDADHVPS-RDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDR--CPPENEMFYGKI-HRGLDRWGGAFFCGSAAVLRRRALDEA----GGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGL----------QPETFASFIQQRGRWATGMMQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4P02.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1172 -6144 -5.24 -26.48 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.55 3D Compatibility (PKB) : -5.24 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.250

(partial model without unconserved sides chains): PDB file : Tito_4P02.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P02-query.scw PDB file : Tito_Scwrl_4P02.pdb: