Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLLSIAISSYNAAAYLHYCVESLVI-GGEQVGILIINDGSQDQTQEIAECLASKYPNIVRAIYQ--------ENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKILETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQYTMMHSLIYRTDLLRASQF 1QGQ Chain:A ((1-185)) -PKVSVIMTSYNKSDYVAKSISSILSQTFSDFELFIMDDNSNEETLNVIRPFLN-DNRVRFYQSDISGVKERTEKTRYAALINQAIEMAEGEYITYATDDNIYMPDRLLKMVRELDT----HPEKAVIYSASKTYHLN---DIVK--ETVRP-AA------QVTWNAPCAIDHCSVMHRYSVLEKV--

General information: TITO was launched using: RESULT: Template: 1QGQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 660 -4570 -6.92 -28.74 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -6.92 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_1QGQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QGQ-query.scw PDB file : Tito_Scwrl_1QGQ.pdb: