Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKIYQKITT-KAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTAVADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGVVKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIP-EDTPAETIA-AMIADEAAIGV---INMKTTAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN------ 5A07 Chain:A ((40-434)) DHDAEVLDSIMDRLHEPLYEKDTF----DPNEVLAENKQLYEEFLLQEISEPKVDNLVRSGDPLA---------GKAKGTILSLV----RNSDLEDIISSIQQLEEEYNKNFGYPYTFLNDEEF---TDEFKDGIKSILPK-DRVVEFGTIGPDN--WNMPDSIDRERYDQEMDKMSKENIQ----YAE-VESYHNMCRFYSK----EFYHHPLLSKYKYVWRLEPNV---NFY-------------CKINYDVFQFMNKN-DKIYGFV-LNLYDSPQTIETLWTSTMDFVEEHPNYLNVNGAFAWLKDNSQN--PKNYDYTQGYSTCHFWTN-----FEIVDLDFLRSEPYEKYMQYLEEKGGFYYERWGDAPVRSLALALFADKSSIHWFRDIGYHHTPYTNCPTCPADSDRCNGNCVPGKFT------PWSDLDNQNCQATWIRHSMSEEELEMY

General information: TITO was launched using: RESULT: Template: 5A07.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1959 53141 27.13 139.11 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 27.13 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.287

(partial model without unconserved sides chains): PDB file : Tito_5A07.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5A07-query.scw PDB file : Tito_Scwrl_5A07.pdb: