Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MSLLETAKRH------QLNSEKYL-----SYLLECLPNEETLVNKEVLEAYLPWTKVV---QEKCK--------- 1UOY Chain:A ((1-64)) DTCGSGYNVDQRRTNSGCKAGNGDRHFCGCDRTGVVECKGG--------------KWTEVQDCGSSSCKGTSNGGATC

General information: TITO was launched using: RESULT: Template: 1UOY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 112 10322 92.16 271.63 target 2D structure prediction score : 0.29 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 92.16 2D Compatibility (Sec. Struct. Predict.) : 0.29 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.185

(partial model without unconserved sides chains): PDB file : Tito_1UOY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UOY-query.scw PDB file : Tito_Scwrl_1UOY.pdb: