Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFAN----QENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTK-DGEIETLSAKDLAFGYRHSAIQES--GAVVLSVKFALAPG-T--H---QV-I------------KQEMDR-LTHLRELK----QP--LEYPSCGSVFKRPVG------------------------------HFAGQLISEAGL-KGYRIGG---VEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR 5JZX Chain:C ((46-404)) ----------FAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTVVRLA-NSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLK--AVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCM----------------

General information: TITO was launched using: RESULT: Template: 5JZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1533 -55894 -36.46 -194.75 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain C : 0.70 3D Compatibility (PKB) : -36.46 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.523

(partial model without unconserved sides chains): PDB file : Tito_5JZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JZX-query.scw PDB file : Tito_Scwrl_5JZX.pdb: