Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTFVDAARSFRTQFDLNFSEKIIVDFFAGGGGASTGLEMGLNRPVYVAVNHNPKAISMHEANHPHAKHYIQDVFAVDPIDICDGHQVGWFHASPDCTHHSQAAGGQPRKKEIRDLSWVVLKFAGKVKPDVISLENVKQILGWGPLIAKRDKATGRVITLDKININGKKVNRIAEPGERVPRHNQFLVPNPKKKGKTWKHFVRSLEQLGYEVEWQKNIIAADFGAPTKRERLFLIARCDGQPI---VWPEKYFSKKPKGNLKKWRSTVECVDFSDLGNSIFDRPQGPLADATLKRIAKGIQKYVIETKEPFFVNSSTPFIGRDFRTSFGHDIREPLATTTAGYGGHSSLISPILVPFITEFANASQQRNWSIDEPLSTICAQVKGGHHGLVTAKLSKDNYKGALRVAAFLINYYGNGDARSITEPMDTITTKDRLVLVTVWIKGEPWAIVDICIRMLKPRELFRAQGVPDSYVIEYGSDGKPLSKKDQVFMVGNSVSPYPMAAIARANNPFITQQIKGAA 5CIY Chain:A ((8-325)) -----------------QLTGLRFIDLFAGLGGFRLALESC-GAECVYSNEWDKYAQEVYEMNFGEK--PEGDITQVNEKTI---PDHDILCAGFPCQAFSISGKQKGFEDSRGTLFFDIARIVREKKPKVVFMENVKNFASHD-------------------------------------------------NGNTLEVVKNTMNELDYSFHAKV-LNALDYGIPQKRERIYMICFRNDLNIQNFQFPKPFEL---------NTFVKDLLLPDSE---V-----EHL---VIDRK-----DLVM--T---------NQE---------------IEQ-----------TTPK-------------------TVRLGIVGK------------------------------GGQ-GERIYSTRGIAITLSAYGGGIF----AK-TGGYLVNGKTRKLHPRECARVMGYPDSYKVH------PS-TSQAYKQFGNSVVINVLQYIAYNIGSSLNFK-----

General information: TITO was launched using: RESULT: Template: 5CIY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1851 -87738 -47.40 -278.53 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -47.40 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.330

(partial model without unconserved sides chains): PDB file : Tito_5CIY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CIY-query.scw PDB file : Tito_Scwrl_5CIY.pdb: