Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQD--LTLDNFMLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFASHG---QM-----------DGMTVSN-VLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD 3Q7K Chain:J ((9-279)) ---------------------LLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVFISIAFVFYITATTGTGAMPYGMAKLIGGICFSLGLILCVICGADLFTSTVLI-VVAKASGRITWGQLAKNWLNVYFGNLIGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKMHHTFIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIPMGIVIRDFATPEFWTAVGSSPESFSHLTVMSFITDNLIPVTIGNIIGGGLLVGLTYWVIYL-------

General information: TITO was launched using: RESULT: Template: 3Q7K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain J - contact count / total energy / energy per contact / energy per residue : 1224 -203956 -166.63 -802.97 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain J : 0.73 3D Compatibility (PKB) : -166.63 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.309

(partial model without unconserved sides chains): PDB file : Tito_3Q7K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q7K-query.scw PDB file : Tito_Scwrl_3Q7K.pdb: