Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTYDAIIIGSGVSGLSAAYGLKE-AGKTVLVVEE---------DLWGGTCPNRGCDPKKVLLSAVEARNRVKQLSGKGFNEI---PTANWEELQKFKRTFTDPVPESRKKQ-LA-EAEIDHLSGTARFLDDSSIEV---------NEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSLPVLPKEIIFIGGGYIAFELATIANAAG---SKVTIVHHNQRPLKEFEASLVEEAVHQMEASGIQFAFGVETQKIIS-EGTRYRLV-GKETELVADMIFCATGRQPNTESLALEQANIVFDKHGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPIIPTIVYASPKLAEVGVTKSHASSS-D--QVVEMDL---TSWFTYHRVNEPVAKAELTFDQ-QNYLIGAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK 1AOG Chain:B ((3-469)) --IFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINK-SYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGVMIKNGGVQVDEYSRTNVSNIYAIGDVT--NRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKV-SGS-KYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSM--

General information: TITO was launched using: RESULT: Template: 1AOG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2493 32007 12.84 74.26 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.72 3D Compatibility (PKB) : 12.84 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_1AOG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AOG-query.scw PDB file : Tito_Scwrl_1AOG.pdb: