Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIMQIRQFQAQRMQAPRDFTPIENTPICVEIGAGKGKHALLFSGQNPQHTLYAIERTREKFLAMQKQHGLEPRDNLIPVHADALPWVVHALYPAQVEHFF-ILYPNP--EPHNPAQRWLNMPFFEFLLSRLKTGGTITLAGNIPEYIEEAEQQLLNVWKLPYQKEKIAQTSARTHFEIKYLERGELCQQLIMTKPEGYNTRFDEFAPLQGQIHVE 3DXZ Chain:A ((35-163)) ------------------------APVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVE-VLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAE-------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3DXZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 527 -51682 -98.07 -430.68 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -98.07 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.373

(partial model without unconserved sides chains): PDB file : Tito_3DXZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DXZ-query.scw PDB file : Tito_Scwrl_3DXZ.pdb: