Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDNLNSPEQSDLSWLTIWSTFLNQAPFTAQTQAPEAACFLQQLIEASLQGDSCIDISPEQIETLGQLVISAEQAKSQVAPCVHDGQGLALYRYWNLEQRLAEQIRRLKQQPIQPVSCEEHLDLLTDPHQRTALQMVTRQSLSIITGGPGTGKTYTLARIIAVLSQAI--PHIRVAMAAPTGKAAQRMQEALQNSFNDPKLLESGLMSDELRN---QSTQTIHRLLGM-GHSQTPRFNQKQPLPYDVIVVDEASMLDLNLATLLFEAVPESCRIILLGDANQLASVDVGAVLADL-------------QQIEALSENRVH----------------LQTSRRFAEGALIGQVARFIQMQTSQIDHEQVLQQFEIDIVQVSELRSIPLEADMPDVVQLEYLPEESPIALETYYQKLMVGFQGYVQSLKAYLQDDHSLEHIENIVKSFDDYRILTAVRHGPFGLQQLNQYAERWLQQQLGIVTL--GGWYVGRPVMMTYNDYQLGISNGDIGLCFEHRTQPQQFEVYFPSLN-KWVAANRLPKSIQSAFALTIHKSQGSEFTHTAVVLDQAAKNLLSQELIYTAITRAKKVVSLLVDPEALLQSFTVRTTRKSGLVEKVNRLVR 5LD2 Chain:D ((155-602)) --------------------------------------------------------------------------------------------------------------------------------QKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLG------KALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAIN-RGDKTAVKTVFQQ------------------DFTDIEKRLLQSGEDYIAM---LEEALAGYGRYLDLLQARAEPDL-------IIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALD-RGQGTRVWFAMPDGNIKSVQPSRLPEH-ETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLA--------

General information: TITO was launched using: RESULT: Template: 5LD2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1899 23998 12.64 58.53 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain D : 0.74 3D Compatibility (PKB) : 12.64 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_5LD2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5LD2-query.scw PDB file : Tito_Scwrl_5LD2.pdb: