Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQRYPMTPEGKIALEKELQHLKTVERPRITQAIAE---AREHGDLKENAEYHAAREQQGFCEGRIQDIEGKLGTAQVIAVKDLEQNGRVV-FGVTVTIENLDTEERNTYKIVGDDEADF--KINKISVNSPIALGLLGKKEGDEVKITTPQGEVEYEVVSVEYL 4WQT Chain:X ((9-154)) ----------KAGYERLMQQLER-ERERLQEISADFEQALEEGDLRENAGYDEARRAMWQNEARIDSLEDILSRAVILE----EGSGEVIGLGSVVELEDPLSGERLSVQVVSPAEANVLDTPMKISDASPMGKALLGHRVGDVLSLDTPKGRREFRVVAI---

General information: TITO was launched using: RESULT: Template: 4WQT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 386 21285 55.14 152.03 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain X : 0.75 3D Compatibility (PKB) : 55.14 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.431

(partial model without unconserved sides chains): PDB file : Tito_4WQT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4WQT-query.scw PDB file : Tito_Scwrl_4WQT.pdb: