Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHF 1X6C Chain:A ((8-92)) WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHF

General information: TITO was launched using: RESULT: Template: 1X6C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 334 -47892 -143.39 -563.44 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 1.00 3D Compatibility (PKB) : -143.39 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 1.00 QMean score : 0.715

(partial model without unconserved sides chains): PDB file : Tito_1X6C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X6C-query.scw PDB file : Tito_Scwrl_1X6C.pdb: