Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WNDG---GFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAW----KFDSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVF 4Y5U Chain:A ((424-513)) WSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQ--IENIQPFSAKDLSIRSLGDRIRDLAQL----

General information: TITO was launched using: RESULT: Template: 4Y5U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 245 12206 49.82 167.21 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 49.82 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.588

(partial model without unconserved sides chains): PDB file : Tito_4Y5U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Y5U-query.scw PDB file : Tito_Scwrl_4Y5U.pdb: