Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence CIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAEN 3CWG Chain:A ((585-664)) -IMGFISKERERAI-STKPPGTFLLRFSESSKEGGVTFTW--------KTQIQSVEPYTKQQLN---FAEIIMGYKIMDATN

General information: TITO was launched using: RESULT: Template: 3CWG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 197 -24146 -122.57 -349.93 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : -122.57 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3CWG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CWG-query.scw PDB file : Tito_Scwrl_3CWG.pdb: