Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAG--QSKLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADASLQDNQQDAPLFAFLQKTLELMEAGL-DYQVLTNIFEIQILTRFGISLNFNECVFCHRV-G-QAFDFSFKYGTCLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQELRQFMDQLYEEYVGIH-LKSKKFIDSLADWGQLLKEEKK 3Q8D Chain:B ((2-233)) ---EGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGR-GEVKTLRSAEAVSLALPLSG--ITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNK----TFT------GRQLKALNAREF----PDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMP----------

General information: TITO was launched using: RESULT: Template: 3Q8D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1025 -39778 -38.81 -176.01 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : -38.81 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.422

(partial model without unconserved sides chains): PDB file : Tito_3Q8D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q8D-query.scw PDB file : Tito_Scwrl_3Q8D.pdb: