Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATC--LSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEEL-SSSYPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAP--HKADVIHQALQTHQLVPQ-QAIIIGDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ 3SD7 Chain:A ((32-230)) ------VLFDLDGTLTDPKEGITKSIQYSLNSFGIKE-DLENLDQFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNGKILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDKDKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVE----------

General information: TITO was launched using: RESULT: Template: 3SD7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 928 5348 5.76 27.71 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 5.76 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_3SD7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SD7-query.scw PDB file : Tito_Scwrl_3SD7.pdb: