Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKLEVKDNKKLVLKSVICKKLHDTKVEDV------DQEINRFHQHLQLLKAQI--FGPLIVKSCGTTIHDDGL------------ITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVRFEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFIPIVSL 1XKQ Chain:A ((42-199)) ----RLEETRQIILKSGVSEKQVNSVVADVTTEDGQDQIINSTLKQFGKIDVLVNNAGAAIPDAFGTTGTDQGIDIYHKTLKLNLQAVIEMTKKVKPHLVASKGEIVNVSSIVAGP-------QAQPDFLYYAIAKAALDQYTRSTAIDLAKFGIRVNSVSPGMVETGF------

General information: TITO was launched using: RESULT: Template: 1XKQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 475 14643 30.83 106.11 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 30.83 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.087

(partial model without unconserved sides chains): PDB file : Tito_1XKQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XKQ-query.scw PDB file : Tito_Scwrl_1XKQ.pdb: